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Forced swimming test. Performances of 26-week-old En1+/− and WT mice in forced swimming test are expressed as the mean ± SD of immobility time during the first (A) and the second (B) test exposure; *p < 0.05 and **p < 0.01. C, Performances in an open field of 24-week-old En1+/− and WT mice tested in FST expressed as the mean ± SD of the distance traveled (in centimeters); *p < 0.05.
