Table 1.

Summary statistics for differential expression in human HD caudate and HD models

	Human HD	R6/2	BDNF HET	BDNF KO	3NP	MPTP
Array type	HG-U133A	MOE430_2	MOE430_2	MOE430_2	RAE230_2	U74Av_2
n HD:controls	26:26	6:6	6:6	6:6	5:5	4:4
# probe sets	22,284	22,690	22,690	22,690	31,099	12,488
% Inc.	10.5	2.2	0.5	2.3	4.5	1.1
% Dec.	8.3	1.9	0.4	2.2	2.1	1.5

Using a consistent analysis method, human HD, HD model, and PD model arrays were separately compared to matched controls to generate profiles of differential gene expression in each system. The type of Affymetrix array, the number of probe sets, and the percentage of probe sets meeting an arbitrary criteria of p < 0.001 for differential expression are displayed for each system. At this level of significance, the expected percentage of false positives would be ∼0.1%. Inc., Increase; Dec., decrease.