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. 2007 Nov 21;27(47):12967–12976. doi: 10.1523/JNEUROSCI.4061-07.2007

Figure 4.

Figure 4.

Effect of Cdk5 cKO on intrinsic membrane excitability of NAc neurons. A, Current–voltage graphs in NAc neurons from control (Con) and cKO mice showing no effect on passive membrane properties. B, Analysis of intrinsic excitability of NAc neurons from control versus cKO mice. The graph shows mean spike number ± SEM in response to different current injections (*p < 0.05, **p < 0.01, ***p < 0.001 compared with control, post hoc Bonferroni, n = 7–8 per group). C, Representative traces of action potential firing evoked by depolarizing current pulses (140–220 pA; 500 ms) in NAc neurons from control and cKO mice. Calibration: 20 mV, 100 ms.