Table 2.
Behavioral effects of intravenous MP in controls and alcoholic subjects and F values for the factorial repeated ANOVA for the group, drug, and interaction effects
Control subjects |
Alcoholic subjects |
ANOVA |
|||||
---|---|---|---|---|---|---|---|
Placebo | MP | Placebo | MP | Group | Drug | Interaction | |
Feel drug | 1 ± 1 | 5 ± 3 | 1 ± 0 | 3 ± 2 | 0.03 | 0.0001 | 0.05 |
Anxiety | 2 ± 1 | 4 ± 3 | 3 ± 3 | 3 ± 2 | NS | 0.005 | 0.05 |
Happy | 6 ± 2 | 7 ± 3 | 8 ± 2 | 6 ± 2 | NS | 0.05 | 0.02 |
High | 1 ± 1 | 6 ± 3 | 1 ± 0 | 3 ± 2 | 0.001 | 0.0001 | 0.002 |
Mood | 7 ± 2 | 8 ± 2 | 7 ± 2 | 6 ± 2 | NS | NS | 0.03 |
Restlessness | 1 ± 1 | 5 ± 3 | 2 ± 2 | 4 ± 3 | NS | 0.0001 | NS |
Stimulated | 3 ± 2 | 7 ± 3 | 4 ± 3 | 5 ± 3 | NS | 0.0002 | 0.003 |
Drug good | 1 ± 0 | 6 ± 4 | 1 ± 0 | 3 ± 3 | 0.03 | 0.0001 | 0.02 |
Drug liking | 2 ± 1 | 6 ± 3 | 2 ± 2 | 4 ± 3 | 0.05 | 0.0001 | 0.05 |
Drug disliking | 1 ± 1 | 4 ± 3 | 2 ± 2 | 7 ± 3 | 0.002 | 0.0001 | 0.05 |
Desire alcohol | 1 ± 0 | 2 ± 1 | 1 ± 0 | 3 ± 3 | NS | 0.005 | NS |
Desire tobacco | 1 ± 0 | 1 ± 1 | 3 ± 3 | 6 ± 4 | 0.0001 | 0.0001 | 0.002 |
Values correspond to means and SDs for the measures obtained 25–30 min after placebo or MP administration.