Figure 5.

A–H, In vivo pathway-specific DTT of intact and injured spinal cords in live common marmosets. MRI and tract-specific DTT of the intact spinal cord (A–D) and hemisected spinal cord 2 weeks after injury (E–H). DTTs of the CST (B, F), spinothalamic tract (C, G), and dorsal column-medial lemniscus pathway (D, H) were conducted in both groups, revealing tract disruption at the hemisection site (C5/6 level) in all pathways. Although there are some limitations, pathway-specific in vivo DTT conducted in live animals yielded results similar to those observed in postmortem animals, especially in respect to major tract morphology.