Table 1.
Electrophysiologic analysis of motor nerves and sensory nerves in Swl/+ and wild-type mice
| Parameters | Units | WT (n = 12) | Swl/+ (n = 13) |
|---|---|---|---|
| MDL | ms | 1.4 ± 0.09 | 1.4 ± 0.08 |
| MPL | ms | 1.9 ± 0.10 | 1.9 ± 0.09 |
| MCV | m/s | 30.1 ± 1.32 | 27.7 ± 1.25 |
| MAmp (D) | mV | 27.0 ± 3.95 | 28.2 ± 3.54 |
| MAmp (P) | mV | 24.8 ± 3.75 | 26.5 ± 3.64 |
| SL | ms | 0.5 ± 0.02 | 0.6 ± 0.03 |
| SAmp | μV | 21.3 ± 1.13 | 14.5 ± 1.30* |
| SCV | m/s | 22.9 ± 0.85 | 20.9 ± 0.97 |
In sciatic nerves, distal latencies (MDL), proximal latencies (MPL), motor nerve conduction velocities (MCV), and distal (D) and proximal (P) compound muscle action potential amplitudes (MAmp) are measured. In sural nerves latencies (SL), sensory nerve action potential amplitudes (SAmp) and sensory nerve conduction velocity (SCV) are measured. Tests are performed in 13-week-old Swl/+ mice and age-matched WT mice. No significant difference is detected between two groups, except that the sensory potential amplitude is reduced by 32% in Swl/+ mice.
*p < 0.01, Mann–Whitney rank-sum test.