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Obese VMH/DMH-specific BDNF mutants have elevated circulating levels of leptin, insulin and glucose. A, Serum leptin levels of AAV2/8-GFP (G) and AAV2/8-Cre (C) mice (n = 7 per group; *p = 0.002). B, Serum insulin levels of AAV2/8-GFP (G) and AAV2/8-Cre (C) mice (n = 7; *p = 0.008). C, Fasted blood glucose levels of AAV2/8-GFP (G) and AAV2/8-Cre (C) mice (n = 7; *p = 0.001). Lean and obese labels refer to body weights of AAV2/8-cre-treated mice at the time of analysis.
