Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2007 Dec 26;27(52):14239–14247. doi: 10.1523/JNEUROSCI.3878-07.2007

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2007 Society for Neuroscience 0270-6474/07/2714239-09$15.00/0

PMC Copyright notice

Figure 3. — Effects of nasal orexin-A (1.0 μg/kg) on DMS performance of alert and sleep-deprived monkeys. Left, There were no significant effects of nasal orexin-A on mean percentage correct (± SEM) performance over all trials. Low- or high-load trials, in the alert (non-sleep-deprived) condition. Right, Effects of 30–36 h sleep deprivation (SD) on performance of monkeys exposed to nasal saline or vehicle spray mist (Saline) 5–10 min before DMS testing. Application of nasal orexin-A spray (1.0 μg/kg) reversed the detrimental effects of 30–36 h sleep deprivation (SD) by significantly improving overall mean percentage correct (± SEM) performance (SD, Nasal Orexin) as well as performance on low-load and high-load trials. **p < 0.001 compared with nasal saline alert; ^‡ p < 0.001 compared with nasal saline sleep deprivation (SD).