Figure 9.

BDNF is required for the morphological maturation of layer 4 PV-immunoreactive cells in somatosensory barrel cortex. A, Neurobiotin staining of PV-positive inhibitory neurons from BDNF(+/+) and BDNF(−/−) mice. Dendrites are shown in black, and axons in are shown in red. Laminar boundaries are indicated by thin green dotted lines and labeled with arabic numerals. B, Quantitative analysis of the number of primary dendrites (left), total dendritic length (middle), and the number of dendritic branches (right) in BDNF(+/+) and BDNF(−/−) mice. C, Total axonal length was also examined but found no difference between BDNF(+/+) and BDNF(−/−) mice. Error bars indicate SEM.