Table 2.

Effect of water deprivation on the distribution of cells expressing Atf4, Cebpb, Creb3l1, Giot1, and Giot2β in the SON and PVN of the control (C) and dehydrated (D) rat hypothalamus

	Atf4		Cebpb		Creb3l1		Giot1		Giot2β
	C	D	C	D	C	D	C	D	C	D
Cells
PVN (magnocellular)	43 ± 4	59 ± 3*	19 ± 2	25 ± 6	20 ± 2	53 ± 3**	13 ± 2	51 ± 2***	41 ± 2	60 ± 5**
PVN (parvocellular)	21 ± 2	32 ± 7	11 ± 1	12 ± 1	16 ± 2	17 ± 2	11 ± 1	16 ± 2	44 ± 3	50 ± 2
SON	41 ± 2	74 ± 3***	13 ± 3	20 ± 2	28 ± 2	42 ± 3**	13 ± 2	49 ± 3***	37 ± 2	59 ± 7*
Grains/cell
PVN (magnocellular)	36 ± 3	93 ± 10**	34 ± 3	31 ± 2	31 ± 2	76 ± 3**	83 ± 11	196 ± 13**	83 ± 8	185 ± 10***
PVN (parvocellular)	30 ± 2	60 ± 8*	28 ± 2	31 ± 5	31 ± 5	70 ± 10*	38 ± 3	39 ± 7	47 ± 4	99 ± 6***
SON	44 ± 4	144 ± 10*	34 ± 2	45 ± 3*	28 ± 3	40 ± 5	47 ± 6	219 ± 9***	85 ± 6	204 ± 10***

Cells in the SON, the magnocellular PVN, and the parvocellular PVN were quantified at 200× magnification while the numbers of silver grains were quantified at 400× magnification.

*p< 0.05

**p < 0.01

***p < 0.001 (unpaired Student's t test). Data are expressed as mean ± SEM. n = 3–4 per group.