Table 1.
Regional A1AR DVt′ (in milliliter/milliliter) and BP2 in control and sleep-deprived subjects
| Region | Control |
Sleep deprivation |
ANOVA | Pairwise | ||
|---|---|---|---|---|---|---|
| Day 1 | Day 2 | Day 1 | Day 2 | p | adjusted p | |
| DVt′ | ||||||
| Frontal ctx | 0.80 ± 0.09 | 0.78 ± 0.08 | 0.77 ± 0.16 | 0.87 ± 0.15 | 0.041 | 0.033 |
| Orbitofrontal ctx | 0.75 ± 0.08 | 0.75 ± 0.06 | 0.72 ± 0.13 | 0.82 ± 0.13 | 0.047 | 0.014 |
| Cingulate gyrus | 0.74 ± 0.09 | 0.75 ± 0.08 | 0.73 ± 0.15 | 0.80 ± 0.15 | 0.118 | - |
| Parietal ctx | 0.78 ± 0.09 | 0.77 ± 0.08 | 0.77 ± 0.16 | 0.85 ± 0.15 | 0.074 | - |
| Occipital ctx | 0.80 ± 0.11 | 0.78 ± 0.09 | 0.80 ± 0.16 | 0.89 ± 0.16 | 0.035 | 0.036 |
| Temporal ctx | 0.76 ± 0.09 | 0.76 ± 0.07 | 0.75 ± 0.14 | 0.84 ± 0.14 | 0.041 | 0.021 |
| Thalamus | 0.77 ± 0.09 | 0.78 ± 0.07 | 0.78 ± 0.16 | 0.86 ± 0.16 | 0.157 | - |
| Striatum | 0.78 ± 0.11 | 0.77 ± 0.07 | 0.79 ± 0.17 | 0.89 ± 0.17 | 0.050 | 0.037 |
| Cerebellum | 0.41 ± 0.06 | 0.40 ± 0.02 | 0.40 ± 0.08 | 0.44 ± 0.08 | 0.127 | - |
| Nucleus basalis | 0.60 ± 0.07 | 0.63 ± 0.10 | 0.63 ± 0.10 | 0.67 ± 0.14 | 0.477 | - |
| BP2 | ||||||
| Frontal ctx | 0.96 ± 0.17 | 0.94 ± 0.18 | 0.91 ± 0.15 | 0.97 ± 0.14 | 0.023 | 0.073 |
| Orbitofrontal ctx | 0.83 ± 0.16 | 0.84 ± 0.13 | 0.77 ± 0.15 | 0.85 ± 0.12 | 0.086 | - |
| Cingulate gyrus | 0.83 ± 0.16 | 0.83 ± 0.16 | 0.78 ± 0.12 | 0.82 ± 0.14 | 0.179 | - |
| Parietal ctx | 0.95 ± 0.15 | 0.92 ± 0.18 | 0.89 ± 0.14 | 0.93 ± 0.13 | 0.038 | 0.203 |
| Occipital ctx | 0.98 ± 0.16 | 0.94 ± 0.20 | 0.97 ± 0.14 | 1.03 ± 0.13 | 0.008 | 0.088 |
| Temporal ctx | 0.86 ± 0.16 | 0.86 ± 0.14 | 0.83 ± 0.12 | 0.89 ± 0.12 | 0.042 | 0.028 |
| Thalamus | 0.89 ± 0.11 | 0.91 ± 0.16 | 0.90 ± 0.15 | 0.95 ± 0.12 | 0.622 | - |
| Striatum | 0.93 ± 0.15 | 0.91 ± 0.12 | 0.96 ± 0.18 | 1.03 ± 0.18 | 0.033 | 0.064 |
| Nucleus basalis | 0.17 ± 0.22 | 0.11 ± 0.17 | 0.13 ± 0.10 | 0.14 ± 0.17 | 0.872 | - |
Values are mean ± SD. ANOVA p, Probability value of a repeated-measures ANOVA for the interaction of the effects day by group; Pairwise adjusted p, multiple-comparison-adjusted probability value of day 1 versus day 2 of the sleep-deprivation group according to the method of Tukey–Kramer; pairwise p is the result of a paired t test of this contrast. ctx, Cortex.