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. 2007 Feb 28;27(9):2403–2409. doi: 10.1523/JNEUROSCI.2916-06.2007

Figure 1.

Figure 1.

Synaptic plasticity in the rat DL striatum is age dependent. After obtaining a stable baseline at an intensity that resulted in a field potential recording of half the maximum amplitude for 10 min, the HFS protocol was given and responses were followed for an additional 30 min. Time courses are presented as normalized PS amplitudes. The inset provides representative traces (average of 12 individual responses) from baseline recordings just before giving the HFS protocol (a), response 30 min after giving the HFS protocol (b), and overlay (a+b). A, HFS caused potentiation of the PS amplitude in P13 animals. The average response 30 min after the HFS was 160 ± 10% SEM (n = 11) of the baseline PS amplitude. B, HFS induced a depression of the PS amplitude in slices made from animals P16–P34. The average response 30 min after the HFS was 53 ± 3% SEM (n = 9) of the baseline measure. Error bars indicate SEM.