Table 2.
Immunolabeling of the NR1 receptor subtype in subregions of the ventral tegmental area and nucleus accumbens of rats subjected to ICES of the lateral hypothalamus or the prefrontal cortex
| Cocaine-stimulated | Cocaine sham-stimulated | Saline-stimulated | Saline sham-stimulated | |
|---|---|---|---|---|
| NR1 in LH-treated rats | ||||
| aNAc | 47 ± 6 | 67 ± 5b | 69 ± 19 | 100 ± 19 |
| pNAc | 160 ± 15 | 132 ± 13 | 97 ± 28 | 100 ± 25 |
| aVTA | 119 ± 19 | 80 ± 7 | 87 ± 9 | 100 ± 9 |
| pVTA | 132 ± 6 | 142 ± 10b | 99 ± 16 | 100 ± 14 |
| NR1 in PFC-treated rats | ||||
| aNAc | 156 ± 42a | 65 ± 15b | 53 ± 16c | 100 ± 25 |
| pNAc | 98 ± 38a | 48 ± 10b | 98 ± 36 | 100 ± 27 |
| aVTA | 95 ± 49 | 78 ± 26 | 151 ± 46 | 100 ± 21 |
| pVTA | 181 ± 87 | 134 ± 36 | 191 ± 59 | 100 ± 20 |
Rats were perfused immediately after the saline challenge. Data are calculated from the mean DAB intensity ± SEM from each subregion of each experimental group.