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. 2007 Feb 21;27(8):1913–1921. doi: 10.1523/JNEUROSCI.4738-06.2007

Figure 3.

Figure 3.

GABA transmission to GnRH neurons increases during the GnRH/LH surge in an estradiol-dependent manner. A, B, Representative sPSC recordings from cells in coronal (A) and sagittal (B) slices from OVX+E mice during negative feedback (top; n = 18 cells coronal; n = 15 sagittal), surge onset (middle; n = 38 coronal; n = 28 sagittal), and surge peak (bottom; n = 18 coronal; n = 26 sagittal). C, D, Mean + SEM sPSC frequency in OVX+E cells in coronal (C) and sagittal (D) slices. Negative feedback (−FB) values in each slice orientation serve as control. *p < 0.05.