CNS inflammation in wild-type and PLP/SOCS1 mice. A–J, Representative images of H&E-stained spinal cord sections: PLP/SOCS1 (A–E) and wild-type (WT) (F–J) mice at day 8 PI (A, F), day 10 PI (B, G), day 12 PI (C, H), day 15 PI (D, I), and day 18 PI (E, J). Arrows point to areas of perivascular inflammation (foci) (B–E, H–J), and the arrowhead points to parenchymal infiltration (J). Scale bar, 100 μm.