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Time course of the effects of streptozotocin treatment on physiological parameters. A, Rectal temperature of 3- to 6-month-old mice (open squares; n = 18–6), and 6-week-old mice (filled triangles; n = 6). B, Plasma glucose and insulin and rectal temperature of a second set of mice (n = 4). Data are means ± SD. The asterisks indicate significant difference as follows: **p < 0.01. N.D., Nondetectable.
