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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Bone. 2016 Sep 4;92:180–188. doi: 10.1016/j.bone.2016.09.001

Figure 6. ECR5 is not required for bone wasting under disuse conditions.

Figure 6.

(A) Representative μCT reconstructions of the distal femur from ground control and tail-suspended wild-type and ECR5−/− mice. (B) Percent change (pre-suspension scan vs. post-suspension scan) in proximal tibia bone mineral content from ground control and tail-suspended wild-type and ECR5−/− mice as measured by serial pQCT scans. Bone volume fraction (C) and trabecular thickness (D) in the distal femur metaphysis as measured by μCT. (E) Relative expression of Sost transcript, normalized to the housekeeping gene Rplp2, in the tibia and femur cortex of ground control and tail-suspended wild-type and ECR5−/− mice. Different letters denote statistical differences among groups. n = 8–10/group for panels B–D; n = 6/group for panel E.