Figure 4.

Synaptic stimulation induces LMO4-mediated transcription via NMDAR and L-VSCC activation. A, Relative CAT activity in E18 dissociated cortical neurons transfected with GAL4-LMO4 and UAS-CAT at 3 DIV and stimulated with either 50 mm KCl or 10 μm glutamate at 5 DIV, as indicated. B, C, Relative CAT activity in E18 cortical cultures transfected with GAL4-LMO4 and UAS-CAT at 3 DIV and treated as indicated at 12–14 DIV. Asterisks indicate significance at p < 0.05. Error bars represent ± SEM.