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Off-beam response is blocked by bicuculline. A, Bicuculline (100 μm) abolishes the off-beam bands and increases the on-beam response evoked by surface stimulation (200 μA, 100 μs pulses at 10 Hz for 10 s). B, Mean ΔF/F for the beam and off-beam band for the example in A. C, Mean ± SD ΔF/F for the on-beam and off-beam band regions before and after bicuculline from four mice. *p < 0.05 denotes a significant change (paired Student’s t test).
