Figure 6.

Responses of GPe and GPi neurons to single (0.7 mA) and burst (10 pulses, 0.4 mA, 50 Hz) Put stimulation recorded after muscimol (0.5 μg/μl, 1.0 μl) blockade of the STN. A, Both single and burst stimulation induced a long-duration inhibition in a GPe neuron (A-a), and local gabazine (0.2 mm, 0.2 μl) application completely blocked the inhibitions (A-b). B, Another GPe neuron induced a similar slow inhibition to both single and burst stimulation (B-a). Local gabazine (0.2 mm, 0.6 μl) application blocked the inhibition to single stimulation, whereas the inhibition to burst stimulation was prolonged although the initiation of the inhibition was slowed (marked by an open arrow in B-b). C, Single and burst stimulation induced a relatively short-duration inhibition followed by a short excitation in a GPi neuron (C-a), which was completely blocked by gabazine (0.2 mm, 0.2 μl) (C-b).