Figure 2.

Repeated amphetamine treatment does not affect steady-state activation or inactivation of mPFC pyramidal neurons. A plot of peak conductance normalized to maximum conductance as a function of test pulse voltage (▪, activation) and peak I_NaT normalized to maximum peak I_NaT as function of prepulse voltage (•, inactivation) with representative current traces of I_NaT and voltage protocols (activation: HP, −70 mV; test pulse, 20 ms from −65 to 0 mV; increments, 5 mV; intertrial interval, 5 s; inactivation: HP, −70 mV; prepulse, 120 ms from −100 to −20 mV; increments, 5 mV; test pulse, 20 mV for 20 ms; intertrial interval, 5 s) is shown. There was no significant difference between groups. Sal, Saline; Amph, amphetamine.