Figure 1.

Effect of CUS on NF-κB activation induced by LPS or saline (SAL) in the frontal cortex (A), hypothalamus (B), or hippocampus (C). Top, Representative EMSA autoradiography. Major specifics (bands 1 and 2) and nonspecific (band 3) DNA interactions are indicated by arrows. Bottom, Densitometric analysis of band 1 (representing p65/p50 heterodimers) presented in the top panel [mean ± SEM; n = 5 animals per group; Bonferroni’s test, ***p < 0.001 vs SAL; ^ap < 0.05 vs control (CON) plus LPS].