Table 3.
Weak dependence of plasticity on equal dissociation constants, Kd, of the CaM·Ng and CaCaM·Ng complexes
Kd (μm)a | 100 Hz | 10 Hz | 5 Hz | 1 Hz |
---|---|---|---|---|
1.0 | 169 | 108 | 69 | 78 |
3.0 | 167 | 108 | 80 | 74 |
5.0 | 165 | 108 | 84 | 73 |
Ng KO | 106 | 100 | 75 | 74 |
Data are EPSPs (percentage) at 60 min after the start of stimulation.
aOther parameters are from the basic set (see supplemental material, available at www.jneurosci.org).