Table 4.
Moderate dependence of plasticity on the total concentration of exchangeable Ng, Ng* = [Ng]0 + [CaM·Ng]0
| Ng* (μm)a | 100 Hz | 10 Hz | 5 Hz | 1 Hz |
|---|---|---|---|---|
| 0.1 | 143 | 107 | 78 | 74 |
| 1.0 | 167 | 108 | 80 | 74 |
| 3.0 | 165 | 108 | 89 | 71 |
| 10.0 | 164 | 108 | 93 | 68 |
Data are EPSPs (percentage) at 60 min after the start of stimulation. Concentration of CaMNg0can be calculated with the following equation: CaMNg0 = CaM0Ng*/(Kd + Ng*) = 0.9Ng*/(3.0 + Ng*), CaM0 = 0.9 μm and [CaCaM] = 0.9 pm in the spine at rest and in the dendrite.
aOther parameters are from the basic set (see supplemental material, available at www.jneurosci.org).