Figure 4.
Recovery from inactivation. The average time course of recovery from inactivation for total INa from small-fast neurons β2+/+ (closed symbols; n = 6) and β2−/− (open symbols; n = 5) is shown. The data were fit with a double exponential (lines) with the following results: for β2+/+, τ1 = 1.3 ± 0.2 ms and τ2 = 95.3 ± 17.8 ms; for β2−/−, τ1 = 1.5 ± 0.5 ms and τ2 = 83.3 ± 29.4 ms. Inset, A representative record from one β2+/+ cell shows INa obtained from recovery intervals of 0.25–30 ms to −120 mV. Error bars indicate SEM.