Histological reconstructions of cannula placements. A, A representative photomicrograph of a coronal section from a rat with chronic infusion of APV. Scale bar, 2 mm. B–G, Schematic illustration of the location of cannula tips in the rats' mPFCs, the rats with acute infusion (B), the 1 d group (C), the 1 week group (D), the 2 week group (E), the second 2 week group (F), and the rats in the electrophysiological study (G). An empty or filled circle represents a placement in the aCSF or APV group, respectively. Numbers to the left indicate stereotaxic coordinates relative to bregma (Paxinos and Watson, 1986).