Figure 1.

Startle amplitudes without prepulses and PPI of the startle reflex in Adcyap1^−/− mice. A–D, PPI levels (top) and startle responses (bottom) at different pulse intensities in 8-week-old mice (A), at 77 dB prepulse followed by 120 dB startle pulses in mice at postnatal weeks 4, 6, and 8 (B), or in 8-week-old mice after pretreatment with haloperidol (C) or amphetamine (D). The number of wild-type (open bars) and Adcyap1^−/− (closed bars) mice are indicated above the bars. Data are expressed as means ± SEM.