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. 2006 Jan 4;26(1):246–255. doi: 10.1523/JNEUROSCI.3858-05.2006

Figure 4.

Figure 4.

p38 MAPK modulates TTX-R Na+ currents. A, Representative time course showing inhibition of basal TTX-R Na+ currents after bath application of the p38 MAPK inhibitor SB202190 (10 μm). Current traces (B) and I–V curves (C) showing the inhibition of TTX-R currents under control conditions (vehicle of 0.1% DMSO) and after SB202190 treatment. D, Grouped data showing the mean percentage change in peak current amplitude over time induced by SB202190 (n = 19) or its inactive control analog SB202474 (10 μm)(n = 8) compared with vehicle (DMSO; n = 13). *p < 0.05 versus the vehicle control, ANOVA.