Table 1.
Amounts of sleep during light (L) and dark (D) cycles after vPAG lesions by 6-OHDA, 5,7-DHT, and ibotenic acid, compared with sham-lesioned control animals
|
|
L-NREM sleep (%) |
L-REM sleep (%) |
D-NREM sleep (%) |
D-REM sleep (%) |
|---|---|---|---|---|
| Control | 58.0 ± 5.3 | 7.2 ± 1.6 | 21.0 ± 3.5 | 5.2 ± 1.9 |
| 6-OHDA | 67.8 ± 7.8* ↑ | 9.5 ± 2.1* ↑ | 31.0 ± 4.2* ↑ | 6.2 ± 1.9 |
| 5,7-DHT | 56.3 ± 1.3 | 7.2 ± 1.0 | 28.0 ± .2.1 | 4.7 ± 0.8 |
| Ibotenic acid |
68.5 ± 8.7* ↑ |
16.0 ± 4.5** ↑ |
34.3 ± 3.0* ↑ |
4 ± 1.4 |
*
<0.05, **<0.01 by t test; ANOVA: L-NREM, p = 4.32 × 106;L-REM, p = 0.0017; D-REM, p = 0.015; D-REM, p = 0.18. Arrows indicate direction of significant difference.