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. 2006 Jan 11;26(2):542–549. doi: 10.1523/JNEUROSCI.3069-05.2006

Figure 7.

Figure 7.

Alix mutants rescue motoneurons from NOCD. A, Ratio of TUNEL-positive cells in the electroporated versus nonelectroporated side of the neural tube. Mean ± SD; n = number of sections analyzed; 12 sections per embryo were counted. **p < 0.001, t test. The number of TUNEL-positive cells was significantly reduced in GFP–Alix-CT- and GFP–Alix-CTΔendophilin-overexpressing embryos. B–D, Evaluation of supernumerary motoneurons on the electroporated side. B, Immunofluorescence staining using an anti-Islet-1 antibody (Bb) on cross section of HH stage 27 chick cervical neural tube electroporated with GFP-Alix-CT (Ba; same section). Scale bars, 40μm. C, Mean numbers ± SD of Islet-1-positive motoneurons supernumerary on HH stage 27 cross sections (B). n = number of sections analyzed; 12 sections were counted per embryo. **p < 0.001, t test. D, Mean numbers ± SD counted after TUNEL staining on HH stage 24 cross sections (see Fig. 6 D).