Figure 2.
DG responses to paired-pulse stimulation applied to the PP: under control conditions, MR or GR blockade did not affect paired-pulse responses (A). B, Strikingly, after stress, there was a decrease in paired-pulse facilitation at 60 ms ISI compared with controls. GR but not MR blockade restored paired-pulse facilitation in the stressed rats (***p < 0.0001). Adrenalectomy restored paired-pulse facilitation as well, presumably because of the lack of GR activation under this condition (traces of MR block and Adx groups are shown under control and stress conditions).