Table 3.
Effect of DSAP lesions on YO-induced Fos activation of DbH-positive NST and VLM neurons
| Medullary region | Intraperitoneal treatment |
Sham controls (n = 9 vehicle; n = 5 YO) |
DSAP rats (n = 10 vehicle; n = 12 YO) |
|---|---|---|---|
| % NA neurons expressing Fos | |||
| cNST | Vehicle | 19.0 ± 6.2 | 48.9 ± 5.8*** |
| YO | 60.7 ± 7.0* | 76.8 ± 2.2** | |
| mNST | Vehicle | 15.6 ± 4.8 | 23.6 ± 3.6 |
| YO | 45.3 ± 4.5* | 53.0 ± 3.0** | |
| rNST | Vehicle | 10.8 ± 4.7 | 8.5 ± 2.9 |
| YO | 45.1 ± 4.8* | 38.8 ± 3.2** | |
| cVLM | Vehicle | 20.3 ± 8.2 | 18.9 ± 5.7 |
| YO | 61.1 ± 8.0* | 52.0 ± 6.1** | |
| mVLM | Vehicle | 25.2 ± 9.1 | 21.0 ± 7.5 |
| YO | 64.6 ± 5.0* | 48.9 ± 3.5** | |
| rVLM | Vehicle | 22.9 ± 8.8 | 11.8 ± 4.7 |
| YO | 64.9 ± 9.8* | 58.7 ± 5.4** |
Vehicle, 0.15 m NaCl; YO, 5.0 mg/kg BW.
*Significantly greater than NA activation in the same medullary region in sham controls after vehicle treatment (p < 0.05).
**Significantly greater than NA activation in the same medullary region in DSAP rats after vehicle treatment (p < 0.05).
***Significantly greater than NA activation within the cNST in sham control rats after vehicle treatment (p < 0.05).