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. 2006 Nov 1;26(44):11487–11500. doi: 10.1523/JNEUROSCI.2364-06.2006

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Copyright © 2006 Society for Neuroscience 0270-6474/06/2611487-14$15.00/0

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Figure 5. — TrkB is located in dendritic filopodia and axonal growth cones. A, Section of a dendrite tipped with a dendritic growth cone from a neuron double immunostained for sTrkB (green) and phalloidin (actin marker; red). Arrows point to sTrkB in dendritic filopodia. B, C, Dendritic filopodia and growth cones of 4 DIV neurons transfected with TrkB-EGFP. TrkB-EGFP is at the tips (arrowheads) of active dendritic filopodia. D, An axonal growth cone from a neuron double immunostained for sTrkB (red) and phalloidin (green). Arrows point to sTrkB puncta found in filopodia of this axonal growth cone. E, F, TrkB-EGFP is present in active axonal growth cones (E) and filopodia (F) (arrowheads). Scale bars, 5 μm.