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. 2006 Oct 11;26(41):10461–10471. doi: 10.1523/JNEUROSCI.2579-06.2006

Figure 2.

Figure 2.

The increase in glutamate uptake during E-LTP and L-LTP is mediated by a Na+-dependent high-affinity glutamate transporter. HFS produced a significant increase in glutamate uptake 7.5 min (A) and 180 min (B) after HFS. TBOA (100 μm), a selective inhibitor of high-affinity glutamate transporters, or Na+ removal during measurement of glutamate uptake inhibited basal uptake as well as the increase in glutamate uptake observed 7.5 or 180 min after HFS. Data were analyzed using a one-way ANOVA (F(5,28) = 75.3, p < 0.001 for A; F(5,24) = 19.3, p < 0.001 for B), and post hoc analysis was done by Tukey–Kramer's test. *Statistically different, p < 0.05. Error bars indicate SEM.