Table 6.

The effect of GDNF on myelination of atrophic MNs

	Adult Bax KO	P21 Bax KO	P14 Bax KO	P1–P14 GDNF	P11–P21 GDNF
L4 ventral root	1847 ± 204 (n = 11)	1742 ± 126 (n = 5)	1440 ± 66 (n = 5)	1949 (n = 1)	2011 ± 80* (n = 4)
Quadriceps	764 ± 58 (n = 10)	732 ± 43 (n = 4)	710 ± 56 (n = 6)	774,737 (n = 2)	797 ± 26 (n = 4)
LGS	271 ± 12 (n = 11)			250,274 (n = 2)	255 ± 12 (n = 4)

Values shown are mean ± SD (number of animals is in parentheses). LGS, Lateral gastrocnemius–soleus.

*p < 0.05, t test, P21 Bax KO versus P21 Bax KO/GDNF.