XRD analysis of S63C myelin

Genotype	Dimensions (Å)					M/(M + B)
	d	cyt	lpg	ext	Δ
WT	175.0 ± 0.17	31	48	47	3.7	0.347
S63C//+/+	174.3 ± 0.23	31	47	49	4.9	0.170
S63C//+/+ (7 h)	173.1 ± 0.12 (218; 6%)	32	46	48		0.152
S63C//+/−	174.9 ± 0.40	31	48	49	4.6	0.208
S63C//+/− (7 h)	173.2 ± 0.40 (204.7 ± 2.26; 41%)
S63C//−/−	210.7 ± 0.23*	33	49	80	12.0	0.127

d, Myelin period expressed as mean ± SEM for n = 4 Bragg order reflections (values in parentheses indicate minor swollen phase and percentage of swollen arrays); cyt, the cytoplasmic separation; lpg, distance between polar headgroups; ext, the extracellular separation; Δ, lattice disorder parameter. M/(M + B) is the ratio of intensity in the reflections of myelin to the total intensity in the diffraction pattern (Avila et al., 2005). Initial 10 min x-ray exposures were recorded <30 min after dissection. The 7 h patterns were 2 h exposures.

*p ≪ 0.001 relative to WT by Student's t test.