Figure 7.

HPLC analysis of DA, DOPAC, and NE in Lmx1bf/f/p and wild-type mice. HPLC analysis of two different monoamines and their metabolites levels in the brain (A) and spinal cord (B) of 2-month-old wild-type (n = 4) and Lmx1bf/f/p (n = 4) mice. There were no significant differences in the levels of DA and its metabolite DOPAC or NE in the brain or spinal cord of Lmx1bf/f/p compared with wild-type mice. C, HPLC analysis of 5-HT levels in the peripheral tissues of wild-type (n = 4) and Lmx1bf/f/p (n = 4) mice. The levels of 5-HT were indistinguishable in the liver and intestine between Lmx1bf/f/p and wild-type mice. Wet weight, Wet tissue weight; WT, wild type.