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. 2006 Nov 29;26(48):12408–12414. doi: 10.1523/JNEUROSCI.3372-06.2006

Figure 3.

Figure 3.

Climbing activity of adult P101L and WT PrP expressing transgenic flies. The climbing assay was measured as described in Materials and Methods using flies that were <1 d old. Thirty flies from each group were examined in 10 consecutive climbing assay tests. Each bar represents the percentage of flies from each group that failed to climb >4 cm in the climbing chamber within 30 s. Asterisks indicate a significant difference between nontransgenic controls and PrP-expressing flies. PRNP;Cha3 and PRNP;Ddc were both heterozygous for PRNP. The χ2 value (df = 1) = 41.71 with p < 0.0001 using a contingency table analysis. NT, Nontransgenic controls; Cha2, GAL4-Cha2; Cha3, GAL4-Cha3; Ddc, GAL4-Ddc. Error bars indicate SEM.