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. 2006 Nov 29;26(48):12387–12396. doi: 10.1523/JNEUROSCI.4316-06.2006

Figure 5.

Figure 5.

The role of CE in the consolidation of auditory fear conditioning. a, Procedural outline. b, STM mean ± SE percentage freezing averaged across all CS presentations. Anisomycin-treated (Aniso) and ACSF-infused animals did not significantly differ. c, LTM mean ± SE percentage freezing averaged across all CS presentations. Intra-CE infusion of anisomycin significantly impaired LTM (*p < 0.001). In contrast, after retraining, animals froze at the same levels as controls. d, Mean ± SE percentage freezing per group during each LTM test CS. All three trials show the same pattern of significance as in c. e, The LTM to STM ratios show that consolidation is significantly impaired after infusions of anisomycin into CE. *p < 0.01. f, g, Mean ± SE percentage freezing during the STM and LTM tests in rats that received intra-PRh infusion of vehicle or anisomycin. h, CE and PRh cannula placements for all animals included in analysis. B, Basal nucleus.