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. 2006 Feb 15;26(7):2022–2030. doi: 10.1523/JNEUROSCI.3218-05.2006

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Copyright © 2006 Society for Neuroscience 0270-6474/06/262022-09$15.00/0

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Figure 5. — Amylin has an excitatory effect on SFO neurons. A, B, Current-clamp recordings showing a depolarization and an increase in action potential frequency induced by the application of 1 nm amylin (gray bar). Note the return to baseline membrane potential and spike frequency after removal of amylin from the bath. C, Mean membrane potential change in the presence of 1 nm amylin (black bar) compared with controls treated with ACSF (white bar); *p < 0.0001. D, Mean peak action potential frequency in the presence of ACSF (white bar) compared with peak frequency in the same cells in the presence of 1 nm amylin (black bar); *p < 0.001.