Figure 9.
Functions directly or indirectly related to basal ganglia activity are not negatively impacted in Ttf1SynCre KO mice. a–e, Locomotor activity in the open field is increased (a), rotarod performance is increased (b), anxiety is increased as assessed by the elevated zero maze (c), and novel location recognition is reduced (d), but novel object recognition is not affected (e). The tests were performed on 14-month-old WT and Ttf1SynCre KO mice. n = 5 mice per genotype. *p < 0.05 versus WT; #p < 0.05 versus old location; ***p < 0.001 versus the two other objects.