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. 2019 Aug 1;14(8):e0211661. doi: 10.1371/journal.pone.0211661

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© 2019 Sanghera et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — Bar graph shows the differences in the distribution of mean serum triglycerides among carriers and non-carriers of missense mutations (S105N, R297Q, and R553W) represented by rs774930016, rs760427565, rs755537970 variants, respectively. Data are shown in mean and standard deviation of means. P values are derived from the general mixed linear models used to test the impact of genetic variants on transformed continuous trait (TG) using the variance-component test adjusted for the random-effects of relatedness and fixed effects of age, gender, BMI and type 2 diabetes. Only association of S105N would remain significant after applying Bonferroni correction.