Table 1. Phenotypic attributes of discovery (sequencing) and replication cohorts as part of Asian Indian Diabetic Heart Study (AIDHS).
| Traits | Discovery cohort (n = 820) |
Replication cohort (n = 1,769) |
||
|---|---|---|---|---|
| HTG cases | Controls | T2D cases | Controls | |
| N | 572 | 248 | 1,074 | 695 |
| Females (%) | 39 | 49 | 44 | 46 |
| T2D (%) | 61 | 53 | N/A | N/A |
| Age (years) | 52.0 ± 12.4 | 55.0 ± 10.6 | 55.0 ± 11.7 | 45.7 ± 14.5 |
| BMI (kg/m2) | 27.6 ± 4.3 | 25.7 ± 4.4 | 27.1 ± 4.8 | 26.0 ± 4.6 |
| TG (mg/dl) | 314.9 ± 134.6 | 78.0 ± 16.9 | 158.1 ± 79.1 | 132.2 ± 67.6 |
| TC (mg/dl) | 203.3 ± 52.3 | 167.2 ± 42.7 | 178.3 ± 46.3 | 184.6 ± 90.2 |
| HDL-C (mg/dl) | 41.1 ± 17.5 | 41.9 ± 14.0 | 40.7 ± 14.1 | 42.6 ± 12.8 |
| LDL-C (mg/dl) | 110.6 ± 43.2 | 106.6 ± 36.2 | 107.9 ± 38.3 | 114.9 ± 35.7 |
HTG- hypertriglyceridemia, T2D-type 2 diabetes, BMI-body mass index, TG-triglyceride, TC-total cholesterol, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol.