Table 1. Brief summary of each cohort including viruses used to infect animals, animal IDs, and animal species.
Indian rhesus macaques were infected by subcutaneous inoculation. Mauritian cynomolgus macaques were infected by mosquito bite unless otherwise noted.
| Cohort | 1° Infection | 2° Infection | Animal ID | Species |
|---|---|---|---|---|
| A | DENV-3 | ZIKV-FP | 850585 489988 321142 |
Indian rhesus macaque |
| B | ZIKV-FP | DENV-2 | 912116 393422 826226 |
Indian rhesus macaque |
| C-1 | DENV-1 | ZIKV-PR | 940262 289427 941637* |
Mauritian cynomolgus macaque |
| C-2 | DENV-2 | ZIKV-PR | 638166 346817 658991 714622 |
Mauritian cynomolgus macaque |
| C-3 | DENV-3 | ZIKV-PR | 644369 865011 359807 753662* |
Mauritian cynomolgus macaque |
| C-4 | DENV-4 | ZIKV-PR | 523664 820832 456891 624311 |
Mauritian cynomolgus macaque |
| negative control | PBS | NA | 774011 829256 875914 |
Indian rhesus macaque |
| DENV control | DENV-2 | NA | rh2484 rh2486 rh2495 rh2499 rh2503 |
Indian rhesus macaque |
| ZIKV control | ZIKV-FP | NA | 448436 756591 861138 411359 912116 |
Indian rhesus macaque |
*Animals were infected by subcutaneous inoculation.