Figure 10.

Normal and transected dhh−/− nerves contain increased numbers of macrophages and neutrophils. A, Comparison of macrophage and neutrophil numbers in intact dhh−/− and null nerves. Note the significant increase in the number of macrophages (p < 0.004) and neutrophils (p < 0.005) in the dhh−/− nerves. B, Comparison of macrophage and neutrophil numbers in the distal stump of dhh+/− and null nerves 2 d after transection. Both normal and mutant nerves show increased macrophage numbers. Transected normal nerves show a substantial increase in neutrophil numbers as expected, but neutrophil numbers in cut dhh−/− nerves are little changed. Mean values ± SEM are shown.