Table 2.
The number of SLIs in double mutants
Dhh+/+/shi+/+ | dhh+/−/shi+/− | shi+/− | shi−/− | dhh−/− | Dhh−/−/ shi−/− | |
---|---|---|---|---|---|---|
Fiber diameter | 7.42 ± 0.10 | 6.94 ± 0.84 | 6.98 ± 0.93 | 7.04 ± 0.93 | 6.86 ± 0.13 | |
8.69 ± 0.22 | 9.03 ± 0.11 | 8.41 ± 0.16 | 9.19 ± 0.16 | 7.96 ± 0.14 | ||
Distance between SLIs | 40.64 ± 1.66 | 27.47 ± 0.95 | 32.44 ± 1.43 | 16.73 ± 0.37 | 13.92 ± 0.38 * | |
41.53 ± 2.04 | 31.64 ± 0.74 | 19.51 ± 0.44 | 23.70 ± 0.73 | 12.90 ± 0.21*** | ||
SLI/100 μm | 2.02 ± 0.11 | 2.89 ± 0.12 | 2.21 ± 0.12 | 4.77 ± 0.17 | 6.42 ± 0.31 * | |
2.36 ± 0.18 | 3.04 ± 0.18 | 4.79 ± 0.20 | 4.17 ± 0.26 | 7.87 ± 0.2*** |
Nerve fiber analysis of the sciatic nerves of littermates of the indicated genotypes at 3 weeks (bold letters) and 15 weeks of age. Note that double null nerves have shorter SLI distances and higher numbers of SLIs per 100 μm than the single mutants.
*p < 0.001 versus shi−/−;
**p < 0.001 versus shi−/− (Mann–Whitney test).