Figure 1.

Chronic THC exposure induced a long-lasting potentiation of basal PF-PC synaptic transmission. A, Representative traces of PF-PC EPSCs recorded at different stimulus intensities, in vehicle (Veh)- and THC-treated mice. Stimulus artifacts were suppressed for clarity. B, Input–output curves for PF-PC EPSCs recorded in cerebellar slices originating from mice chronically exposed to THC or to its vehicle. Asterisks indicate significant differences (p < 0.01). Values are expressed as mean ± SEM.