Table 2. Cox proportional hazard models for overall mortality.
| Variable | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age group, year | ||||
| <50 | 1.000 | 1.000 | ||
| 50–59 | 0.970 (0.600–1.568) | 0.902 | 1.483 (0.911–2.413) | 0.113 |
| 60–69 | 1.527 (1.022–2.280) | 0.039 | 2.124 (1.417–3.186) | <0.001 |
| 70–79 | 2.974 (1.963–4.506) | <0.001 | 3.167 (2.088–4.801) | <0.001 |
| Sex | ||||
| Female | 1.000 | 1.000 | ||
| Male | 1.039 (0.758–1.425) | 0.810 | 1.200 (0.833–1.730) | 0.328 |
| Education | ||||
| Elementary school or none | 1.000 | 1.000 | ||
| Middle or high school | 0.722 (0.530–0.983) | 0.038 | 1.145 (0.813–1.613) | 0.438 |
| College or higher | 0.616 (0.369–1.029) | 0.064 | 1.204 (0.675–2.148) | 0.529 |
| Unknown | 1.354 (0.800–2.291) | 0.259 | 1.705 (0.998–2.911) | 0.051 |
| Smoking | ||||
| Never smoker | 1.000 | |||
| Former smoker | 1.098 (0.766–1.573) | 0.612 | ||
| Current smoker | 1.284 (0.912–1.808) | 0.152 | ||
| Unknown | 0.000 (0.000–0.000) | 0.959 | ||
| Alcohol consumption | ||||
| Never drinker | 1.000 | 1.000 | ||
| Former or current drinker | 0.800 (0.595–1.076) | 0.139 | 0.783 (0.559–1.096) | 0.154 |
| Family history of gastric cancer | ||||
| Absence | 1.000 | 1.000 | ||
| Presence | 0.581 (0.394–0.858) | 0.006 | 0.767 (0.513–1.145) | 0.194 |
| Helicobacter pylori infection | ||||
| Absence | 1.000 | |||
| Presence | 1.163 (0.825–1.641) | 0.389 | ||
| Unknown | 0.816 (0.570–1.169) | 0.268 | ||
| TNM stage | ||||
| I | 1.000 | 1.000 | ||
| II | 3.209 (2.134–4.827) | <0.001 | 3.315 (2.200–4.996) | <0.001 |
| III | 5.505 (3.818–7.939) | <0.001 | 5.722 (3.960–8.266) | <0.001 |
| IV | 36.474 (22.875–58.158) | <0.001 | 36.860 (22.853–59.452) | <0.001 |
HR, hazard ratio; CI, confidence interval; TNM, tumor-node-metastasis