Figure 7.

Epileptiform field potentials (EFP) in CA1 stratum pyramidale of dko mice. A, Spontaneous epileptiform field potentials (CA1, stratum pyramidale) occurred only in slices from dko mice (representative trace) but not in slices from wt mice (data not shown; p = 0.001). B, Low-intensity Schaffer-collateral stimulation gave rise to EFP only in dko slices (representative sample trace) but not in slices from wt mice (data not shown) (p = 0.007). C, EFP induced by washout of Mg²⁺ (0 Mg²⁺) were more frequent in dko slices and occurred with shorter latency. Original traces of a wt (top) and dko (bottom) slice.