Table 1.

Cosinor analysis of the circadian rhythm of ingestion in Ucn-2 knock-out mice and their wild-type littermates

	Female		Male
	Wild type	Ucn-2 KO	Wild type	Ucn-2 KO
Water intake
Amplitude (μl/h)	383 ± 54	234 ± 24*	254 ± 42	201 ± 58
MESOR (μl/h)	304 ± 54	254 ± 23	206 ± 26	215 ± 40
Peak (μl/h)	686 ± 101	488 ± 28*	462 ± 65	415 ± 93
Nadir (μl/h)	−79 ± 42	19 ± 38	−47 ± 30	14 ± 37
Acrophase (h after dark onset)	3.6 ± 0.5	3.9 ± 1.1	5.9 ± 0.1	4.6 ± 1.4
Cosinor fit (r)	0.75 ± 0.05	0.73 ± 0.07	0.83 ± 0.02	0.76 ± 0.06
Food intake
Amplitude (mg/h)	116 ± 16	102 ± 11	124 ± 24	102 ± 6
MESOR (mg/h)	163 ± 12	160 ± 12	163 ± 12	186 ± 19
Peak (mgl/h)	280 ± 6	262 ± 18	287 ± 32	288 ± 17
Nadir (mg/h)	47 ± 28	58 ± 15	40 ± 20	83 ± 21
Acrophase (h after dark onset)	3.7 ± 0.8	3.5 ± 0.7	4.6 ± 0.6	3.5 ± 0.8
Cosinor fit (r)	0.78 ± 0.07	0.85 ± 0.04	0.90 ± 0.02	0.90 ± 0.02

*p < 0.05 versus WT.